Cancer is a worldwide leading cause of death, being brain in the top 10 of cancer mortality, in the group of highest per-patient initial cost, and in the list of devastating prognosis and least available solutions. Tumor degree of resection fully correlates with life expectation, but using only surgeon“s hability, complete resection rates may be as low as 18%. Electromagnetic properties of human tissues presents a defined behavior that may be used for tumor detection, enabling intraoperative tumor resection monitoring. Such probe will require millimeter wave range on-chip micromachined features for signal transmission, routing, and processing, and on-tip GFET detectors, to mitigate calibration and noise issues. This project will use electromagnetics theory, microfabrication techniques, and graphene transistor technology to develop a probe for intraoperative tumor resection monitoring, featuring a multimodal image fusion, to guide surgeons to reduce the residual tumor sizes.